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Interventional Radiology

The advantages of Interventional Radiology

is a specialized branch of radiology that uses mostly minimally invasive, image-guided techniques to diagnose and treat various medical conditions, offering effective alternatives to traditional surgical treatments.

With over 20 years of experience, our team specializes in the minimally invasive treatment of complex multi-organ tumors.

How it works

Interventional Radiology uses radiological images, such as CT or ultrasound, to guide minimally invasive instruments directly to the affected area. Procedures are usually performed under local anesthesia or sedation, depending on the complexity and location of the tumor.
Featured Treatments

Our Services

Our expertise includes therapies such as tumor ablation (thermal and non-thermal), percutaneous biopsy, and complex bone stabilization to address structural fragility caused by metastatic disease.

Innovative medical technique used to destroy tumor tissue by freezing it.

Innovative medical technique used to destroy tumor tissue by freezing it.

Innovative medical technique used to destroy tumor tissue by freezing it.

Cryoablation

Innovative medical technique used to destroy tumor tissue by freezing it.

Electroporation

Non-thermal tumor ablation near critical anatomical structures.

Thermoablation

Consectetur adipiscing Heat-based destruction of tumors using Radiofrequency or Microwaves.

Complex and Multi-Organ Tumor Treatments

Integrated solutions for advanced or anatomically complex cancers.

Bone Stabilization and Local Bone Disease Control

Relieving pain, preventing fractures, and restoring stability in weakened bones.

For Doctors

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For Patients

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Meet Our Specialists

Get to know our experienced specialists dedicated to delivering advanced oncologic care.

Claudio Pusceddu

Interventional Oncologic Radiologist

Interventional oncologic radiologist with over 30 years of experience, specifically dedicated to multi-organ cancer treatment, including lung, breast, kidney, liver, adrenal glands, bone, neck, and pancreas, using a wide spectrum of advanced and complex image-guided techniques.

Salvatore Marsico

Interventional Oncologic Radiologist

Interventional oncologic radiologist with a focused expertise in multi-organ cancer treatment, and a particular specialization in spinal and musculoskeletal interventional radiology.

case studies

Explore Patient Stories

Read real experiences from our patients

We are very grateful to the pediatricians of this clinic! Excellent service and timing. We will be coming soon for a scheduled checkup and hopefully will find the same doctor.

Brian Woods

Patient
See how we make a difference

Watch Our Procedures in Action

Experience our precision-driven, minimally invasive treatments in action, designed to enhance patient care and outcomes.

Cryoablation

Minimally invasive freezing technique for precise tumor destruction

This technique has been applied successfully in over 600 cases, especially in patients with limited or no remaining treatment options . In breast cancer, cryoablation offers a superior patient experience compared to radiofrequency due to its pain-free nature and same-day discharge. In select cases, it is also feasible and effective for pancreatic and craniofacial bone tumors. 

Cryoablation is an advanced interventional radiology technique that eliminates tumor cells by exposing them to extreme cold (below -20°C), followed by a controlled thawing phase. This freeze–thaw cycle causes thermal shock that leads to irreversible cell death. The procedure is performed percutaneously under image guidance (CT, ultrasound, or MRI), using cryoneedles activated by argon gas.

It is particularly suited for patients who are not candidates for surgery or when tumors are located close to critical structures like nerves, the spinal cord, or the skin—areas where traditional heat-based ablation would be too risky. Cryoablation is used successfully in treating tumors in the lungs, kidneys, liver, bone (including spine and skull), breast, pancreas, mediastinum, adrenal glands, and head and neck.

Key Advantages:

  • Nearly painless; often done under local anesthesia.
  • Can treat large tumors (up to or over 10 cm) in one session.
  • Visual control of the «ice ball» ensures precise targetin.
  • Allows simultaneous treatment of multiple tumor sites.

Electroporation

Non-thermal tumor ablation near critical anatomical structures
Irreversible Electroporation (IRE) is a novel technique that uses high-voltage electric pulses to permanently disrupt cancer cell membranes without generating heat. It is especially useful in treating tumors located near vital structures such as blood vessels, bile ducts, or nerves, where thermal ablation methods pose significant risks.

The procedure is performed percutaneously under precise imaging control and does not damage the extracellular matrix, which helps preserve the functionality of surrounding tissues.

Clinical Benefits:

  • No thermal injury to adjacent critical structures.
  • Ideal for tumors in anatomically challenging sites (e.g., pancreas, porta hepatis).
  • Preserves healthy tissue architecture.
  • Expands curative options for patients with locally advanced disease.

IRE is a valuable tool in our multidisciplinary approach, offering hope to patients previously considered untreatable due to tumor location.

Thermoablation

Heat-based destruction of tumors using radiofrequency or microwaves
Thermoablation involves using focused thermal energy to destroy tumor cells. The most commonly used modalities are radiofrequency ablation (RFA) and microwave ablation (MWA). These procedures are image-guided and minimally invasive, typically performed under sedation or local anesthesia.

Thermal ablation is highly effective for tumors that are difficult or impossible to remove surgically. It is frequently used in treating primary and metastatic tumors of the liver, lungs, kidneys, thyroid, uterus and bones. MWA is often preferred for larger lesions because of its ability to deliver higher and deeper heat more quickly.

Key Advantages:

  • Minimally invasive with low complication risk.
  • Short recovery time.
  • High efficacy in local tumor control.
  • Can be combined with other treatments like vertebroplasty.

Thermal ablation is part of a broader toolkit that includes combination procedures for enhanced patient outcomes, especially in difficult anatomical locations or in palliative care.

Complex and
Multi-Organ Tumor Treatments

Integrated solutions for advanced or anatomically complex cancers
For patients with advanced-stage, multifocal, or anatomically complex tumors, we offer individualized treatment strategies that combine multiple minimally invasive techniques in a single session. These may include cryoablation, thermal ablation, cementoplasty, and image-guided biopsy or drainage.

Such integrated procedures reduce the need for repeated hospital visits, lower the cumulative procedural risk, and provide effective palliation or tumor control even when conventional therapies have failed.

Common Indications:

  • Multiple metastases across organs or bones.
  • Tumors involving spine, pelvis, or skull base.
  • Complex cases unsuitable for surgery or radiation alone.

Benefits of Combined Approach:

  • Fewer sessions and anesthesia events.
  • Coordinated treatment plan across specialties.
  • Enhanced symptom relief and local tumor control.

This holistic approach represents the forefront of interventional oncology, blending innovation with compassion for patients in need of tailored care.

Bone Stabilization and Local Bone Disease Control

Relieving pain, preventing fractures, and restoring stability in weakened bones.

This category includes procedures like vertebroplasty, kyphoplasty, and cementoplasty, which involve injecting bone cement (PMMA) into bones compromised by tumors, fractures, or osteoporosis. These techniques are often performed under CT or fluoroscopic guidance, ensuring precision and safety.

They are highly effective in managing pain from metastatic bone disease, reinforcing skeletal stability, and preventing further structural deterioration. Combined with radiotherapy or ablative techniques, they offer comprehensive control over local disease.

Key Procedures:
  • Vertebroplasty 
    Minimally invasive injection of bone cement into fractured vertebrae to stabilize the bone and significantly reduce pain.
  • Vertebral Implants 
    Mechanical devices used to reconstruct and support the vertebral body, often followed by cement injection to restore stability and alignment.
  • Kyphoplasty 
    Similar to vertebroplasty, but includes balloon inflation to restore vertebral height and correct spinal kyphosis before cement injection.
  • Cementoplasty (Extra-Spinal) 
    Cement augmentation techniques applied to non-vertebral bones—such as the pelvis, femur, or humerus—to reduce pain and reinforce structural integrity in oncologic or osteoporotic lesions.
  • Percutaneous Osteosynthesis 
    Image-guided insertion of screws or hardware to stabilize pathological fractures or prevent impending fractures in weakened bones.
  • Combined Procedures: Cementoplasty + Thermal Ablation 
    Integration of bone cement injection with thermal ablation (e.g., radiofrequency or microwave) to achieve both tumor control and structural support.
  • Percutaneous Discectomy (Dekompressor Technique) 
    Minimally invasive decompression of herniated intervertebral discs using a mechanical device to relieve pressure on spinal nerves and reduce symptoms. 

These interventions are fast, safe, and provide significant improvements in patient quality of life—often with same-day discharge.